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Capsule filling · Industry glossary

Capsule capacity

The volume specified as available for a capsule fill, normally expressed in millilitres.

Also called: capsule volume; nominal capsule volume; body volume; fill capacity.

Body fill volume and total internal volume

Powder-fill capacity, liquid-fill capacity and total internal capsule volume can be listed separately, even for the same shell size. Check which quantity a capacity chart reports before using the number.

A larger total internal volume does not mean that the whole figure is available as the intended powder dose. Do not combine a body-volume value from one chart with a total-volume value from another as if they were equivalent.

How do you convert capsule volume to mg?

For an estimate, multiply the usable fill volume in mL by the formulation’s relevant fill density in g/mL, then multiply grams by 1,000 to express the mass in mg. Volume is space; mg is mass.

The density must describe the powder state relevant to the filling process. A loose bulk-density result and a tapped-density result are not interchangeable promises of the mass a machine will deliver.

Estimated fill mass (mg) = fill volume (mL) × fill density (g/mL) × 1,000

Nominal capacity and actual filling performance

The calculation can check whether a volume-and-density claim is internally consistent. It cannot demonstrate stable dosing, the final locked condition or actual fill-weight variation. Those are separate questions for the intended formulation and filling arrangement.

IN THE PRODUCTION LINE

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